Detalhe da pesquisa
1.
Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity.
Cell
; 177(3): 597-607.e9, 2019 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31002796
2.
Whole-exome sequencing identifies rare genetic variants associated with human plasma metabolites.
Am J Hum Genet
; 109(6): 1038-1054, 2022 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35568032
3.
Circulating metabolites modulated by diet are associated with depression.
Mol Psychiatry
; 28(9): 3874-3887, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37495887
4.
Metabolomic differences in lung function metrics: evidence from two cohorts.
Thorax
; 77(9): 919-928, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34650005
5.
The blood metabolome of incident kidney cancer: A case-control study nested within the MetKid consortium.
PLoS Med
; 18(9): e1003786, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34543281
6.
The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis.
PLoS Med
; 17(10): e1003394, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33064751
7.
Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies.
Metabolomics
; 14(10): 128, 2018 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30830398
8.
Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.
JAMA
; 320(24): 2553-2563, 2018 12 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30575882
9.
Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.
PLoS Med
; 13(11): e1002179, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27898682
10.
Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis.
JAMA
; 316(13): 1383-1391, 2016 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27701660
11.
Plasma Metabolites Related to the Consumption of Different Types of Dairy Products and Their Association with New-Onset Type 2 Diabetes: Analyses in the Fenland and EPIC-Norfolk Studies, United Kingdom.
Mol Nutr Food Res
; 68(1): e2300154, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38054622
12.
Causal effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation study.
EBioMedicine
; 88: 104441, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36696816
13.
Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases.
Nat Genet
; 55(1): 44-53, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36635386
14.
Development and validation of a metabolite score for red meat intake: an observational cohort study and randomized controlled dietary intervention.
Am J Clin Nutr
; 116(2): 511-522, 2022 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35754192
15.
The Relationship of Maternal Gestational Mass Spectrometry-Derived Metabolites with Offspring Congenital Heart Disease: Results from Multivariable and Mendelian Randomization Analyses.
J Cardiovasc Dev Dis
; 9(8)2022 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36005401
16.
Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma.
Nat Med
; 28(4): 814-822, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35314841
17.
Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution.
J Clin Endocrinol Metab
; 107(4): 1065-1077, 2022 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34875679
18.
Rare and common genetic determinants of metabolic individuality and their effects on human health.
Nat Med
; 28(11): 2321-2332, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36357675
19.
Plasma metabolites to profile pathways in noncommunicable disease multimorbidity.
Nat Med
; 27(3): 471-479, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33707775
20.
Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the GIPR Region.
Diabetes
; 70(11): 2706-2719, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34426508